Update:
I took out the stock champion plugs that have roughly 5k miles on them since I put them in and gapped them down to .35 and screwed them back in.
Took the plug wires off of the coil end this time, I don't remember if I did this when I replaced the plugs this last summer or not. I noticed that the #4 wire output terminal on the coil had a little bit of a black residue built up on it so I cleaned all of it off back down to a nice shiny finish.
I loaded up both ends of each wire with di-electric grease.
As a matter of personal preference I replaced the vacuum line that I had ran from the rear of the compressor housing after realizing I had at first installed a 5/32". I replaced it with a 7/32" line still keeping the supplied AGP bleed in the line. This time instead of of zip ties for that particular vacuum line I put some small diameter worm screw clamps. This was probably a bit overkill as far as the clamps are concerned, but I had them laying around extra and decided what the hell.
Now for the part that matters, the test drive. Unfortunately I was unable to get a great deal of testing done due to the weather turning a bit wintery and slick today. I was however able to get a couple of decent 4th and 5th gear pulls with the engine under a bit of load without having to worry about traction quite so much. Before if I was cruising down the interstate at 70 mph in 5th gear and climbed on the gas anything much past half throttle it would start to miss and run like crap. Today after messing with the items listed above the car never missed a beat.

I believe this to be mostly due to the things I repaired on the ignition system and not so much changing out the vac. line, but hey who knows.
I will do some further testing this week after the weather and road conditions clear up a bit and report back with my findings after having access to 2nd and 3rd gear again. As for now the car appears to be fixed, but I am not going to get my hopes way up until I am able to fully recreate the conditions that caused my intial concern.